Low Dose Naltrexone (LDN) is a popular alternative treatment not only for psoriasis. Still the most people do not get it and are clueless about the reasons why and how Naltrexone in low dosages works for so many chronic inflammatory and degenerative diseases.
Many doctors, chiropractors and naturopaths agree that LDN is quite an effective and relatively very safe treatment for many diseases.
Since I am absolutely sure that psoriasis is an Autonomic Nervous System dysfunction rather than autoimmune disease (or some form of immune disease) I do agree that potent drug like Naltrexone may improve or even completely clear up psoriasis.
Naltrexone affects the neurons substantially so there is a chance of improvement of psoriasis.
I say a chance because it is relatively easy to guess the biochemistry outcomes of the immune system compared to guessing the biochemistry outcomes of nervous system.
But what if the secret power of Naltrexone lies somewhere else?
What if it is not about its direct effects on the nervous system?
How does naltrexone exactly contribute to improvement of psoriasis?
One theory is that taking this drug which blocks the opioid receptors makes the brain produce own endorphins because it “thinks” that there is an endorphin deficiency.
But if you think about this theory it sounds kind of weird.
If the opioid receptors were blocked with Naltrexone then what purpose would the endorphins serve?
And are they (endorphins) even anti-inflammatory? Maybe and maybe not!
The researchers found out that one of the endogenous endorphins – beta-endorphin – affected the inflammation differently in two inbred rat strains.