Adrenal Fatigue Scam or How to Cure Stress

Psoriasis going hand in hand with adrenal fatigue is a well known fact. A lot of people with psoriasis consider stress the single biggest contributing factor to their psoriasis.

Can psoriasis and adrenal fatigue be cured?

Yes stress can be cured. The common underlying problem with the whole stress problem, anti-stress supplements and avoiding stressful situations in not understood at all. The solution lies in resolving the underlying cause what is bad perception of stress by our bodies – physiologically. It is not only about our psychological mindset, it is about the biochemistry that runs deep in our cells that make us stressed out by any minor stressful situation.

I am always trying to differentiate between “stressful situations” which you can avoid and the “perception of stress” when you are unfortunately encountered with some “stressful situation”.

That “perception of stress” is very dysregulated in condition which is misleadingly called “adrenal fatigue” – what actually means that adrenals are not able to quickly and in the right way respond to the environmental changes – “stressful situations”. It is the same as when you are tired you are angry over anything what results in the “stress (as physiologically detrimental and immunosuppressive state of the matter)” for your body. So we should make the differences between the “stressful situations” and the body abilities to “perceive the stress the right way” and eventually the “stress” as the result for our physical body (cells).

HPA axis controls it all

Most of us who consider ourselves stressed are not just stressed but also in vicious circle of chronic HPA axis dysregulation due to deficiencies, infections and mostly our diet and bad digestion. Bad digestion and high polysaccharide diet is what causes the fungal overgrowth what leads to blood sugar swings and eventually may end up as HPA axis dysfunction or “adrenal fatigue” what is really bad term in my opinion.

I mean if your HPA axis (cooperation of hypothalamus-pituitary-adrenals) does not work properly then even the minor stressful situation or situation when you need to decide about something will make you really stressed out, even makes you sweating, your hart racing and you will be shaking. It is not because that situation is so bad – it is because your body is not capable to decide what is so bad and what is not.

It is the same as if you are in rush and suddenly it is difficult to do things that you can do without any problem usually. It is because of all those stress related hormones in your blood that can make you easily fight or run but not to concentrate on more complicated things that need more brain capacity and thinking.

However many people likely most of them say that their psoriasis developed in stressful period of their lives or shortly after. This is also another clue that would suggest psoriasis as immune deficiency rather than overreactive immune system. Stress is extremely immunosuppressive not the opposite. And I think that suppressed immune system is just like bad as hyperactive/overreactive immune system.

Although we have to differ between the overreactive immune system and too strong immune system. Having the overreactive immune system does not always mean strong immune system – like in case of allergies. But the truth is that if you have a lot of inflammatory cytokines in your body – you may experience less seasonal infectious illnesses.

Stress hormones in psoriatics vs healthy people

There is one interesting study from Iran where researchers studied the significance of stress related hormones in people with psoriasis. The study “THE SIGNIFICANCE OF STRESS HORMONES IN PSORIASIS” [1] concluded this (excerpt from the abstract):

“…Whilst the pathogenesis of psoriasis is not known, psychological stress has been
implicated as a potential trigger in the onset and exacerbation of the condition.

As activation of the hypothalamic pituitary adrenal axis (HPA)
is critical to a successful stress response, we investigated this in patients with psoriasis. This study was
performed on 55 patients (40 females and 15 males) visited our clinic for treatment of psoriasis in
pharmacology department. We measured the rate of activation of HPA by hormonal changes. These
patients displayed higher fasting blood sugar (FBS), epinephrine (Ep), adrenocorticotropin hormone
(ACTH), aldosterone, prolactin, growth hormone and estradiol hormones value but diminished cortisol
and corticotropin releasing factor (CRF). These results show that HPA and psychoneuroendocrine
hormones have a significant role in psoriasis.”

Image source: F. Z. Zangeneh and A. Fazeli. THE SIGNIFICANCE OF STRESS HORMONES IN PSORIASIS. Acta Medica Iranica 2008; 46(6): 485-488.

As the authors write – ACTH hormone is the best marker for endocrine stress. It reaches the maximum level in the first hour of stress so it is better indicator than the cortisol which is at its highest

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