Probiotics are Useless, Saccharomyces Boulardii as SIBO Cure

In psoriasis there is an overgrowth of bacteria and fungi in small intestine caused by low bile flow, low pancreatic and villi enzymes that leave the starches undigested.

The fact is that antibiotic therapy is not successful, too. Mostly when taken for short period of time like days or weeks. That fact establishes the bacteria as not the number one cause of psoriasis. Or maybe I should say – easily reachable bacteria – are not the top cause of psoriasis.

Bacteria are usually covered in biofilm in the small intestine or in the tissues and successfully hidden in root canal teeth.

Cure Small Intestinal Bacterial Overgrowth with more bacteria???

Why would anybody wanted to take another billions of bacteria in capsules – probiotics?

There is no known research that would concluded high cure rate of psoriasis with some probiotic bacteria.

Then why all those websites, blogs and “experts” recommend probiotics – lactic acid bacteria or those expensive soil based – for treatment of small intestinal bacterial overgrowth? Do they even know how the body works?bugs

Small intestine should be clean – without bacteria – or at least almost clean with bacteria content of 1 000 bacteria per milliliter (CFU/ml). That is actually pretty clean environment!

So why would you take billions of bacteria in capsule and even support their growth with apple pectin or some other fiber?

One probiotic capsule of 10 billion bacteria (CFU) is equivalent of maximal bacterial count that should be in 10 000 liters of fluid from small intestine. Human small intestine contains about 45 – 319 ml of fluid in fasting state and 20 – 156 ml one hour after meal. [1]

That means one capsule of 10 billion bacteria contains about 50 000 times more bacteria than there should be in small intestine.

Probiotic bacteria should live only in colon

Now you got the point?

The probiotics you taking are not intended for small intestine. They should not colonize the small intestine at all. Their destination is colon.

The problem of small intestine in SIBO is low bile flow and too much bacteria. But not just bacteria – fungal growth – is the consequence of low stomach acid, low bile flow and low enzymatic output of pancreas and intestinal villi.

Fungus can be defeated with another fungus – Saccharomyces boulardii

This fungal specie is popular for dysbiosis because it has very low pathogenicity and is not invasive. The point is that Saccharomyces boulardii fungus will compete with bacteria and mostly other fungi in the small intestine! [2]


Fungus under microscope. Weak body allows the spores to grow in the blood and tissues.

The other fungi may be very dangerous to human health because they may produce various toxins like aflatoxin, ochratoxin, fumonisin,… that disrupt the hormonal system, damages the neurons and are carcinogenic.

Keep in mind that you may be having the die-off or detox symptoms when taking Saccharomyces boulardii. Every supplemental fungus as well as probiotic bacteria may cause problems in some cases so any serious bad reactions should be communicated with professional!

How can be SIBO cured

Small intestine dysbiosis should be addressed with choleretic/cholagogue supplements like bile acids or artichoke. Restoring the proper bile flow is essential in order to clear up and heal the small intestine and cool off the inflammation.

Artichoke (leaf) is one of the best choleretic and cholagogue herbs.

Artichoke (leaf) is one of the best choleretic and cholagogue herbs.

Saccharomyces boulardii may greatly help with this because it inhibits the growth of bacteria and other fungi in the small intestine.

Probiotic bacteria in capsules in many cases are surely not the best choice especially in the beginning of the process. SIBO resolves after stomach restores the acid production and liver the bile flow.

1) C. SCHILLER, C.-P. FROHLICH, T.GIESSMANN, W.SIEGMUND, H.MONNIKES, N. HOSTEN and W. WEITSCHIES. Intestinal fluid volumes and transit of dosage forms as assessed by magnetic resonance imaging. Aliment Pharmacol Ther 2005; 22: 971–979.

2) Kelesidis T, Pothoulakis C. Efficacy and safety of the probiotic Saccharomyces boulardii for the prevention and therapy of gastrointestinal disorders. Therapeutic Advances in Gastroenterology. 2012;5(2):111-125.

11 Responses

  1. Hans says:

    The title is useless: Saccharomyces boulardii IS a probiotic… LOL

    • John says:

      I have got 3 messages for you:

      1) Your are right!

      That’s why I use the term “bacterial probiotics” now.

      2) “Probiotics” is a term commonly used for bacterial probiotics.

      So everybody knows what I mean by that title.

      3) Thank you for your comment!

      • Kathleene Parker says:

        John, I can’t quite agree on your final assertion. I, too, was confused by the title. So, no, not “everyone” knows. I’d say something like what you said about probiotics–for me, they INCREASED my pain–with something like, but S. B. is an exception!

  2. Ivo says:

    Hi, just wondering what data did you update in 2017? Also, do you know any success stories from people with SIBO. The more I look, the more I only find people that went trough one of the programme, felt better, than relapsed.

    This does seem like a more holistic solution, as I feel that SIBO, whose symptom is IBS, is a disease. But you’re the only one (so far that I’ve found) that mentions causes of the disease and how to deal with them.

    Thank you!

    • John says:

      What data did I update in 2017? Do not understand exactly what you mean?

      You mean the latest research or my opinion on SIBO?

      You now why people relapse?

      Because they do not care about the cause – low bile flow.

      Without bile even the best diet will fail.

      Artichoke leaf extract, ox bile, lecithin, b-vitamins, Nystatin, oregano oil, protein supplement (whey protein isolate)…

      There is plenty of info in my recent articles – most of them are paid, though.

      • Ivo says:

        It says at top of article “BY JOHN · PUBLISHED APRIL 2, 2015 · UPDATED MAY 28, 2017”, so I just wondered what the new info is.

        Thank you for the reply!

  3. Alice says:

    what is the cause of low bile flow? how this cause can be addressed for it to permanently shift to normal bile flow?

    • John says:

      The cause is usually inflammation (liver inflammation perhaps as well as liver overload) and overall nervous system imbalances. Artichoke leaf extract, lecithin, ox bile, ursodeoxycholic acid (can be prescribed by doctor), B-complex (!!!).

  4. I have SIBO, and it’s awful! I have bought Saccharomyces Bouldarri , but am not sure how much to take or when. Also, I don’t have a gallbladder. My ejection fraction was so low, they had to remove it.
    Can you help direct me? It would be awesome to eat again and not be swollen and in pain!

  5. Kathleene Parker says:

    This information is SO important. If I had just been told this a long time ago… HOWEVER, as one who has walked around with SEVERE SIBO for decades, I submit that ONLY a multi-faceted, aggressive program of Rifaxan–as the commercial says, “Accept no substitutes!”–with the “correct” program for advanced-stage SIBO is 2 weeks, 2 weeks off, and repeat 2 more times, plus follow-up breath tests and possible re-treatment, will work. It’s pricey, but if you’re fighting for your life…: Plus, there must be exclusion of particular triggers (dairy, wheat (i can do NO grains but rice, which isn’t really a grain.), soy, oils other than olive) and egg) at least until healed, and low-FODMAP, for me, the rest of my life with a few exclusions that somehow are okay. Also, where is reference to ENZYME therapy? Long before I FINALLY got my diagnosis (Thanks to my persistence, more than doctor expertise.) I learned that top-quality digestive enzymes did miracles. In fact, if I get into a trigger food, my eyes often water and try to swell shut (Fun!), but 3 or 4 Transformation digestive enzymes (They have no beet fillers!) will have things clamed in minutes. Also, I’d love to hear your input on taking ox bile and OTHER SUPPORTS for the broad physiology you define, again, in what must happen for unfortunates like me who were (1.) given HUGE, PROLONGED amounts of antibiotics and then, after years of struggling and the onset of major symptoms, another medical goof, YEARS of high-level proton-pump inhibitors, OR medicines way to throw more gasoline on the fire. Thanks so, for your re-enforcement!

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