Psoriasis Severity is Correlated With the Fibrinogen Levels

From the beginning of this blog I claim that psoriasis is caused by low oxygen levels in the body and skin. I say the cause or at least huge contributing factor is thick blood what causes bad blood flow mostly in the microvessels which are naturally so narrow that even one red blood cell must be really flexible to go through it.

Fibrinogen – inflammation and thick blood

What role does the fibrinogen play in psoriasis pathogenesis?

Well, fibrinogen is a glycoprotein synthesized in liver which is converted to fibrin by thrombin during the coagulation process. Fibrin together with the platelets form the blood clot during some injury like when you cut your finger.

23.fibrin400xFibrin is your friend in cases like acute injury but sometime may become an enemy because a lot of fibrin formation leads to thickening of the blood and even thrombosis. Thick blood caused by high generation of fibrin strands is by some researchers suspected as the underlying factor contributing to many diseases like CFS, fibromyalgia, depression, anxiety, worsening of eyesight, tinnitus, fungal infections of the skin, nail fungus, Crohn’s disease, bad digestion, …

The authors of one study in Turkey measured the inflammatory markers and associated hypercoagulability in patients with psoriasis.

The scientists concluded that “although not reaching statistical significance, the fibrinogen levels for the study group were higher” than in control group.

The scientists were clever enough to point out that fibrinogen levels were higher in psoriatics even though statistically were not high enough.

And that’s why we should not believe in statistics so much.

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