Hypoglycemia Causes Psoriasis, Night Sweating, Peeing, Insomnia and Anxiety

There are so many people with psoriasis complaining about night sweats and waking up to go to pee. And most of them are almost ultimately without any clue what causes it.

When they go to see a doctor the answer they usually get is “anxiety due to psoriasis” and less common answers are infection, prostate problems or even possibly some cancer. The major problem with that answer is that anxiety does not cause night sweats.

It is the hypoglycemia which causes anxiety, psoriasis as well as nigh sweats.

If the doctors prescribe the antidepressants for suspected anxiety which is caused by adrenaline (due to hypoglycemia) the health can go just downhill. It may ease the anxiety but those drugs won’t do anything good for the real cause of anxiety and night sweats – for hypoglycemia.


  • anxiety is often caused by constant excess of adrenaline
  • hypoglycemia causes constant adrenaline release
  • hypoglycemia is very common problem but still doctors consider it as rare
  • emotional stress must be avoided in order to heal the body
  • nutrition is essential – magnesium, B-complex, lecithin, zinc, omega 3,6,9
  • hypoglycemic diet is the best way to heal
  • whey protein concentrate or isolate before sleep may greatly reduce the hypoglycemia during the night

Really Bad Digestion, Hunger, Aggressiveness and Psoriasis

Recently I have got the next question from one reader of this blog…


I have a long-term psoriasis with associated problems like bad digestion when I have a gas after every meal no matter what I eat.

I do not think I have a dental infection at this point.

I am hungry and have to eat every 3 hours because otherwise I feel weak. I must eat something sweet to bring the energy back.

I also feel often depressive and get aggressive.

I want to try artichoke, sunflower lecithin, B-complex, omega 3 supplement, magnesium and I would also like to try something for my blood sugar levels.

Do you think some amino acids and protein supplement would be OK since I am very skinny?

What do you think about an ayurvedic supplement – Triphala – for digestion?



I am not a doctor so these are just my thoughts.

If there is a gas after eating “whatever” then probably even the basic starches are not digested properly.

Being hungry and craving to eat sugar (sweet foods) may indicate hypoglycemia, insulin resistance (caused usually by infection – SIBO, yeast/fungal or dental infection) and deficiencies (mostly B-vitamins).

Depression and aggressiveness is usually accompanied/caused by hypoglycemia.

Depression is caused by more like long-term hypoglycemia over months or years.

Adrenaline makes the body unresponsive to its effects (to normal levels of adrenaline) and this may cause depression.[1, 2] It is a known fact that administration of adrenaline “cures” depression in seconds. But his effect lasts just a few minutes or maybe hours.

There is not a lot of research in this field but many people have experienced the feeling how they get stimulated in some “fight” situations where adrenaline is being released by the body in huge amounts.

Aggressiveness is strongly linked to adrenaline – everybody knows that – so not much to say here. It is a fight-or-flight hormone and neurotransmitter.

Blood sugar imbalances are usually caused by infection (SIBO, dental infection) and deficiencies like those of B-vitamins but chromium improves insulin resistance as well.

The point is to eat hypoglycemic diet – brown rice, fat and protein with meals,… protein shakes are really good.

Sadly, the foods like brown rice have their advantages over white rice in terms of being hypoglycemic, but are harder to digest and may feed the bacteria (SIBO) more during the time they are moving through the intestines.

Another problem may be in those who have really messed up digestion that they can get less energy of those foods due to low absorption of those foods. White rice is more like pure starch so it is easier to digest than brown rice which has still a bran on its outer shell.

The causes of Being skinny

There is a lot of causes why some people and especially those with some chronic inflammation are skinny.

1) SIBO creates a lot of problems in the body:

– overgrown bacteria eat your protein before you digest it!

– hormonal imbalances and catabolic state of the body (cortisol, lactic acidosis…)

– bad digestion = bad absorption of nutrients

2) B-vitamin deficiencies
3) Other deficiencies – vitamins and mostly minerals
4) Stressful

20 Responses

  1. Anon says:

    Hi John. You said “”The key is protein; the higher needs for protein in people with hypoglycemia and eating standard diets may lead to weight loss due to protein deficiency. That is why quality protein supplement like whey protein concentrate (WPC) or whey protein isolate (WPI) may do wonders for those people.

    High protein food or protein supplement before sleep may balance the blood sugar and make the sleep more refreshing due to avoiding the hypoglycemic state during the night.””

    Are these whey proteins you mention just the standard protein powders that you mix up into a protein shake? Are you recommending 1 serving before going to bed? FYI, Although I am thin,I don’t have a problem with losing weight. But do have trouble getting to sleep and staying asleep.

    • John says:

      Yes, I talk about those like the bodybuilders use.

      About 30 grams is one serving and you should buy good quality WPC or WPI with amino acid content of 75% or more.

      Eating maybe 1 hour before sleep may help; it is just a myth to go to sleep with an empty stomach!

      • Dee says:

        Hi John,
        Have insomnia sleep problems and distruptions. Like getting up to pee 3 times during the night,. I find it hard to go to sleep, and waking up in the middle of the night, because I have high cortisol and glucose at night. Is there anything I can take. Right now I tried all the relaxing sleep teas, take Seriphos, Gaba and l-tryptophan, and melatonin. Still I wake up and do not get enough sleep. I am 68 yrs. old. I am a petite thin person so have no need to lose weight. Are there any natural supplements I can take to heal this cortisol problem. Thanks for your help.


        • John says:

          High cortisol is probably due to hypoglycemia and high glucose is because there is probably insulin resistance caused by inflammation.

          I mean – there is not a cortisol problem. There is probably hypoglycemia/insulin resistance and that is what may be causing high cortisol.

          Dental infections – infected teeth (and root canals) – very often cause the inflammation which leads to insulin resistance and insulin resistance leads to hypoglycemia.

          Or inflammation may be caused by endotoxins from the small intestine. Read my posts about bile flow – artichoke leaf, lecithin, B-complex, bile acids…

          What are the basic supplements for hypoglycemia?:
          – B-complex – Jarrow B-Right
          – chromium
          – magnesium

          But as I said, hypoglycemia is insulin resistance caused usually by inflammation induced by endotoxins.

          • Maggie McCall says:

            Hi, I do hope you do not think I am interfering. I think the above post is spot on. I just wanted to say what helped me to sleep, and that is orange juice, not a huge amount, with 1/2 a Tsp of Himalayan salt in, and 2 ml of ionic magnesium Chloride. I have this by the bed at night and when you wake for a pee in the night have a few sips , enough to send you back to sleep. also have some just before you go to bed, have some sips every time you go to bed, . Apart from obviously trying to sort out your inflammation. Hope this helps.

  2. Michelle says:

    You mentioned above that 30 grams is one serving-would this also be the same for my daughter who is almost 11 and weighs 85 lbs? I am hoping that something like this would help her bed wetting.

    • John says:

      The RDA for protein is established at 0.8 grams per 1 kg (2.2 lbs) of body weight. People who train a lot like bodybuilders or some athletes have their protein intake at 2 grams per 1 kg of body weight or even higher.

      We are talking about the daily protein intake in foods (meat, eggs, milk,…) + supplements (protein shakes) together. So 100 kg athlete does NOT drink 200 grams of protein powder daily.

      The Whey Protein Concentrate or Whey Protein Isolate supplements have about 72-85% of protein per weight. The rest is sugar (lactose), fat (from milk) and additives.

      For 85 lbs person according to the RDA the total amount of protein per day would be 30 grams. This amount of protein is in about 40 grams of whey protein concentrate/isolate.

      If I was 85 lbs person I would take 20 grams of protein powder which contains about 15 grams of pure protein.

  3. Rosemary says:

    At nearly 60 now, if I have ‘any’ drink after 9pm, its guaranteed to get me up for a pee in the night. why is this pls? If I were to follow your suggestion and drink HP shakes, I would be up have the night with disturbed sleep rhythms

    • John says:

      Wake up to go to pee is something else than wake up due to hypoglycemia induced adrenaline release and spasms in urinary bladder.

      You can try to eat protein containing food before sleep so it does not have to be necessarily the protein shake.

      And protein shake (30 grams of powder) can be mixed in just as little as 100 ml of water so you can minimize the need to pee during the sleep. And still you can try drink the shake before 9pm.

  4. Sally says:

    Hi John will nuts do the job to keep us asleep? Ive had stress and insomnia for ten years.not slept through the night for ten years and trying hard to fix

    • John says:

      The best way to find out is to eat some and you will know.

      Some people need to eat starches before sleep and some will do fine with protein shake or nuts.

      It really depends on many factors including the digestive capabilities – how fast the food is digested, how much enzymes is your body able to produce, how much you will eat,…

      Generally I consider whey protein concentrate and isolate as the great supplements because a lot of people today are protein deficient. Amino acids found in whey protein are crucial for whole body and all functions.

      That is why the sleep may significantly improve not just immediately that night but also a few weeks (2-3 weeks) later as the body gets the missing amino acids and re-start the processes which were down-regulated due to amino acids deficiency.

  5. Asia says:

    Do metformin is helpful in the early treatment of the hypoglycemia?

    • John says:

      I do not know what you mean by “treatment”? I am not a doctor so I can not say you if it is helpful.

      There is not 1 case of hypoglycemia worldwide that would be caused by metformin deficiency so I would say that metformin can not cure hypoglycemia.

      If anything it might cause hypoglycemic episodes (even though less often than some of the other diabetic drugs).

      Metformin suppresses the glucose production in the liver and this has nothing to do directly with hypoglycemia caused by endotoxins, TNF-alpha and inflammation.

      Resolving the cause of inflammation like deficiencies and infections (tooth decays and root canals, SIBO) and avoiding the emotional stress is I believe the only surefire way to recovery from chronic health issues.

      In some cases and in some health problems the drugs are very effective during the recovery so I am not against their use without any exception. But as I said I am not a doctor so I am not saying to anybody to take the drugs or not to take them.

  6. Janet says:

    I like your answer to the above question. My first impression was that the person in question was celiac. Celiac can cause depression and poor digestion. I also thought this person has other food sensitivities to cause problems in the stomach.
    I will be tested the end of next month for allergies with blood and urine. I have so many food allergies.

    Glad to have you back. Janet

    • John says:

      Thank you for your comment!

      I think that there is a big hype regarding the celiac disease.

      There is really not so many people who have celiac disease.

      Being somehow intolerant to gluten, wheat or/and other grains does not make a person celiac.

      Inflamed small digestion will cause a lot of problems – digestive, immune, nervous,…

      Small intestine inflammation lead to leaky gut and person may and often will react to many foods because it is like having the food particles (proteins) administered under the skin or into the blood.

      Ultimately it is all about the liver and how much burden it can take care of. Once the liver can not keep up with the rate of endotoxins, chemicals, food proteins… which leak through the intestines into the body that is the point when problems start to appear.

  7. Patti says:

    So glad to see you posting again John and thank you for all your hard work.. My question pertains to what supplement to use to support the liver. Milk thistle is always the go to remedy for the liver but if it causes excess estrogen then what is the alternative? Again, thanks for all you do.


    • John says:


      There is a lot of other options instead of Milk Thistle.

      Antioxidant properties have a lot of natural substances. Berries, beetroot, broccoli, cabbage,… but keep in mind that if you decide to juice the vegetable like broccoli it may be easy to take too much! I would not drink 1 liter of broccoli juice daily like some people might want to.

      There are still many supplements – artichoke leaf extract, Alpha Lipoic Acid, lecithin, Liv.52 (formula consisting of a few herbs/plants), lecithin, Ursodeoxycholic acid (need prescription usually), Turmeric, N-Acetylcysteine, Barberry, Dandelion,… and even the essential oils.

      I did not check every supplement/herb mentioned above for its possible estrogenic effects but I doubt that any would have as strong as Milk Thistle.

      Keep in mind that estrogen-like compounds have most if not all plants – even wheat. It is not just soy which has estrogenic isoflavones in it.

      How much of them and how strong those estrogen-like compounds are is what really matters. Milk Thistle is not worthy for liver in my opinion, especially for men.

  8. Brad says:

    Hello. I have been diagnosed with reactive hypoglycemia. When I wake up I have a strong urge to urinate. After being asleep about 5 to 6 hours, I start having anxious, frustrating, repetitive dreams that Cause me to wake up exhausted. If I go back to sleep, this cycle of crazy dreams continues. Thinking about setting an alarm for six hours after I go to sleep, to wake up and drink a protein shake to prevent this. I am definitely having all the symptoms of the adrenal release.
    Your thoughts?

    • John says:

      Drinking a protein shake before even going to sleep might help.

      Resistant starch intake improves the hypoglycemia as well.

      Do you take B-complex? LifeExtension BioActive Complete B-complex taken about 1 hour before sleep significantly improves the hypoglycemia.

      Hypoglycemia, insulin resistance, gut inflammation, endotoxins… a vicious circle. Read the articles.

  9. Jennifer says:

    I was diagnosed with hypoglycemia 20 years ago. I just have to say thank you, after reading this article I feel reliveved!!

    Four months ago I began waking up every night between 3-4am drenched in sweat and what I presumed was anxious; Dr’s tried treating my sleeplessness and anxiety with two different kinds of anxiety medication (not at the same time) and a sleep aid. None of which helped, nor I continue to take, however I continue to have this issue.
    My husband suggested it was my hypoglycemia that was causing my sleeplessness, sweating and anxiety so I started digging deeper on how this annoying disease could further continue to impeed my life. I have found quite a bit of information, including your article, that supports my husbands theory!

    Hopefully figuring out how to maintain healthy blood sugar levels while I sleep will help with my issues!
    Thank you for the information!

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