Psoriasis and Acidic Blood: The Cause Is Deficiency of B vitamins

Lactic acidosis is often caused by biotin or thiamine deficiency. The role of B-vitamins is still underrated by most people including those with psoriasis. We have a huge promotion of magnesium, zinc, vitamin C, … but where are the B-complex vitamins? I think that generally the most important thing in healing of psoriasis is proper intake of B-vitamins.

If you want to get all of the B-vitamins even those who are no longer considered as vitamins you should take brewer’s yeast or what is even better – beef liver.

Even though our bodies are able to synthesize some chemicals (including those who are no longer considered as B-vitamins) that does not mean it is not important or (sometimes) inevitable to provide them in the food we eat.

Not just that we need the minerals and other vitamins to make some very important non-essential chemicals but everybody is unique and we have various genetic variations (I prefer word variation over mutation) which may prevent us from producing or processing some important molecules efficiently and in sufficient amounts.

Of course, B1 (thiamine) and B7 (biotin) deficiencies are not the only possible causes of lactic acidosis but they are well documented. Overall nutrition is important and elimination of unnecessary toxins (including the various drugs) is advised.

Symptoms of Lactic acidosis

You may ask why I write about lactic acidosis?

Well, I believe that lactic acidosis is very common in people with many chronic diseases including psoriasis.

The thing with lactic acidosis is that it develops when there is some metabolic problem affecting the production of energy from glucose.

The symptoms of lactic acidosis include nausea, vomiting, general weakness and others.


In psoriasis I believe that there is a shortage of oxygen which prevents the production of energy molecule – ATP. This leads to increased formation of lactate which flows through the bloodstream.

That’s the reason why I say that drinking calcium carbonate, magnesium oxide, sodium bicarbonate, chlorella, green barley, lemon juice and other “alkalizing miracles” in order to cure the acidity does nothing really useful.

These alkalizing measurements with sodium bicarbonate have their place in acute situations when there is a severe lactic acidosis but administration of sodium bicarbonate still it does not cure the lactic acidosis. [4]

Biotin deficiency and lactic acidosis

One of the genetic variations affecting the blood pH levels is biotinidase deficiency which belongs to the group of multiple carboxylase deficiency disorders.

The scientific paper from 1981 describes the multiple carboxylase deficiency which presented in early childhood as alopecia, skin rashes, dermatitis, hypotonia (muscle weakness), ataxia and motor retardation, frequent episodes of ketoacidosis with hyperlactatemia.

On high protein diet the symptoms of propionic and methylcrotonic aciduria appeared as well. These are the organic acids which levels are elevated in states of impaired energy production in cells.

The plasma biotin levels were found to be significantly lower than in control subjects.

The symptoms disappeared after the administration of biotin.[1]

Most B-complex supplements have biotin in them but some people may make better use of adding the additional supplement containing higher dose of biotin per capsule.


Thiamine deficiency causes lactic acidosis

A report presents a case of 56 years old man with lactic acidosis whose symptoms rapidly improved after intravenous administration of thiamine.

Patient consumed the alcohol regularly (which is a risk factor of thiamine deficiency) and shortly before the hospitalization lost about 5 kg. [4]

In acute deficiency, pyruvate accumulates and is metabolized to lactate, and chronic deficiency may cause polyneuropathy and Wernicke encephalopathy. Classic symptoms include mental status change, ophthalmoplegia, and ataxia but are present in only a few patients. Critically ill patients are prone to thiamine deficiency because of preexistent malnutrition, increased consumption in high-carbohydrate nutrition, and accelerated clearance in renal replacement.

Thiamine deficiency may become clinically evident in any type of malnutrition that outlasts thiamine body stores (2 to 3 weeks), including alcoholism, bariatric surgery, or hyperemesis gravidarum, and results in high morbidity and mortality if untreated.
” [4]

As you can see the body has stores of thiamine only for about 3 weeks so consider this if somebody tells you how great it is to have 1 months water fast. It is similar also with some other

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2 Responses

  1. Rachael says:

    I just found this article after search for “thiamine psoriasis”. I have developed severe psoriasis after many years of struggling with ill health and bad digestion. I also have problems with my heart related to POTS Syndrome and PVST which I have read is caused directly by a thiamine deficiency. Since I was raised on junk food and soda growing up, I am almost certain that I developed this deficiency in childhood.

    I was just wondering what the connection is to thiamine deficiency and psoriasis , since I didn’t see it in your article.

    Also, I was shocked to see that lactic acidosis is related to thiamine deficiency since I have been experiencing burning and inflammation in my arms and face for well over a year now. Some internet searches suggested that it might be a sign of lactic acidosis. Now I am convinced that it is.

    Is there a specific test that I request from my doctor to determine if I am indeed suffering from lactic acidosis poisoning?

    Thanks so much for your time and information! God bless you. 🙂

    • John says:

      Psoriasis just like the most others chronic inflammatory diseases DO NOT have only ONE cause.

      But most of them share the same biochemical processes in the background, just the symptoms are different – Inflammation Causes The Symptoms We Call Diseases

      In one person it can be a B-vitamin deficiency (like thiamine) in other person it may be vitamin B3 deficiency, in other case it may be smoking (nicotine intake may make the nicotinic acetylcholine receptors quite unresponsive), or it may be choline deficiency, low bile flow due to gallstones, infected tooth,…

      Thiamine, specifically is involved in energy production (Krebs Cycle) and acetylcholine production –
      Subclinical Vitamin Deficiencies and Neurotoxins

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